Invitrogen™ ACVRL1 Recombinant Rabbit Monoclonal Antibody (8L2V7)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA538212

Catalog No. PIMA538212

Description

Positive Samples: 293T, Mouse spleen, Mouse kidney, Rat heart Immunogen sequence: VLWEIARRTI VNGIVEDYRP PFYDVVPNDP SFEDMKKVVC VDQQTPTIPN RLAADPVLSG LAQMMRECWY PNPSARLTAL RIKKTLQKIS NSPEKPKVIQ.

Activin A receptor type II-like 1 (ACVRL1) is a type I cell-surface receptor for the TGF-beta superfamily of ligands. ACVRL1, similar to other type 1 receptors, has a conserved serine-threonine kinase subdomain, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. Mutations in ACVRL1 are associated with hemorrhagic telangiectasia type 2. Mutations in ACVRL1 have been linked to Fibrodysplasia Ossificans Progressiva (FOP), a rare genetic disorder characterized by the formation of bone in muscles, tendons, and other connective tissues, as well as Epicanthus.

Specifications

• Antigen: ACVRL1
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P37023, P80203, Q61288
• Gene Symbols: ACVRL1
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 404-503 of human ACVRL1 (P37023).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Western Blot, Immunocytochemistry
• Clone: 8L2V7
• Conjugate: Unconjugated
• Gene: ACVRL1
• Gene Alias: activin A receptor like type 1; activin A receptor type II-like 1; activin A receptor type IL; activin A receptor, type II-like 1; activin A receptor, type II-like kinase 1; Activin receptor like kinase 1; activin receptor-like kinase 1; activin receptor-like kinase-1; Acvrl1; Acvrlk1; AI115505; AI427544; ALK1; ALK-1; HHT; HHT2; ORW2; R3; R-3; Serine/threonine-protein kinase receptor R3; SETHKIR; SKR3; TGF-B superfamily receptor type I; TSR-I
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11482, 25237, 94
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov