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Invitrogen™ ACVRL1 Recombinant Rabbit Monoclonal Antibody (8L2V7)
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Catalog No. PIMA538212
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100 μL
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PIMA538212 100 μL
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Catalog No. PIMA538212 Supplier Invitrogen™ Supplier No. MA538212
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Description

Rabbit Recombinant Monoclonal Antibody

Positive Samples: 293T, Mouse spleen, Mouse kidney, Rat heart Immunogen sequence: VLWEIARRTI VNGIVEDYRP PFYDVVPNDP SFEDMKKVVC VDQQTPTIPN RLAADPVLSG LAQMMRECWY PNPSARLTAL RIKKTLQKIS NSPEKPKVIQ.

Activin A receptor type II-like 1 (ACVRL1) is a type I cell-surface receptor for the TGF-beta superfamily of ligands. ACVRL1, similar to other type 1 receptors, has a conserved serine-threonine kinase subdomain, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. Mutations in ACVRL1 are associated with hemorrhagic telangiectasia type 2. Mutations in ACVRL1 have been linked to Fibrodysplasia Ossificans Progressiva (FOP), a rare genetic disorder characterized by the formation of bone in muscles, tendons, and other connective tissues, as well as Epicanthus.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ACVRL1
Applications ELISA, Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone 8L2V7
Concentration 0.8 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene ACVRL1
Gene Accession No. P37023, P80203, Q61288
Gene Alias activin A receptor like type 1; activin A receptor type II-like 1; activin A receptor type IL; activin A receptor, type II-like 1; activin A receptor, type II-like kinase 1; Activin receptor like kinase 1; activin receptor-like kinase 1; activin receptor-like kinase-1; Acvrl1; Acvrlk1; AI115505; AI427544; ALK1; ALK-1; HHT; HHT2; ORW2; R3; R-3; Serine/threonine-protein kinase receptor R3; SETHKIR; SKR3; TGF-B superfamily receptor type I; TSR-I
Gene Symbols ACVRL1
Host Species Rabbit
Immunogen Synthetic peptide.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11482, 25237, 94
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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