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ACY1 Mouse anti-Human, Clone: OTI16C1, lyophilized, TrueMAB™

Mouse Monoclonal Antibody
Supplier: OriGene CF503228

Description
Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO
ACY1 encodes a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and an acyl group, and has been postulated to function in the catabolism and salvage of acylated amino acids. This gene is located on chromosome 3p21.1, a region reduced to homozygosity in small-cell lung cancer (SCLC), and its expression has been reported to be reduced or undetectable in SCLC cell lines and tumors. The amino acid sequence of human aminoacylase-1 is highly homologous to the porcine counterpart, and this enzyme is the first member of a new family of zinc-binding enzymes. Mutations in this gene cause aminoacylase-1 deficiency, a metabolic disorder characterized by central nervous system defects and increased urinary excretion of N-acetylated amino acids. Alternative splicing of this gene results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ABHD14A (abhydrolase domain containing 14A) gene. A related pseudogene has been identified on chromosome 18.Specifications
ACY1 | |
Monoclonal | |
Unconjugated | |
ACY1 | |
ACY-1, ACY1D, HEL-S-5 | |
Mouse | |
Affinity Chromatography | |
RUO | |
95 | |
-20° C, Avoid Freeze/Thaw Cycles | |
Lyophilized |
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot | |
OTI16C1 | |
PBS with 8% trehalose and no preservative; pH 7.3 | |
Q03154 | |
ACY1 | |
Full length human recombit protein of human ACY1 produced in HEK293 cell. | |
100 μg | |
Primary | |
Human | |
Antibody | |
IgG1 |
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