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Invitrogen™ ADAM15 Recombinant Rabbit Monoclonal Antibody (4T4X10)
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Catalog No. PIMA535694
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PIMA535694 100 μL
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Catalog No. PIMA535694 Supplier Invitrogen™ Supplier No. MA535694
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Description

Rabbit Recombinant Monoclonal Antibody

Immunogen sequence: RHIRRRRDVV TETKTVELVI VADHSEAQKY RDFQHLLNRT LEVALLLDTF FRPLNVRVAL VGLEAWTQRD LVEISPNPAV TLENFLHWRR AHLLPRLPHD S.

The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ADAM15
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Recombinant Monoclonal
Clone 4T4X10
Concentration 3 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Adam15
Gene Accession No. O88839, Q13444, Q9QYV0
Gene Alias a disintegrin and metallopeptidase domain 15 (metargidin); a disintegrin and metalloprotease domain 15 (metargidin); a disintegrin and metalloproteinase; a disintegrin and metalloproteinase domain 15; a disintegrin and metalloproteinase domain 15 (metargidin); AD56; ADAM; ADAM 15; ADAM metallopeptidase domain 15; Adam15; ADAMs; CRII-7; disintegrin and metalloprotease 15; disintegrin and metalloproteinase domain-containing protein 15; Mdc15; MDC-15; metalloendopeptidases; Metalloprotease RGD disintegrin protein; metalloproteinase-like, disintegrin-like, and cysteine-rich protein 15; metargidin; tMDC VI; tMDCVI
Gene Symbols Adam15
Host Species Rabbit
Immunogen Synthetic peptide.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11490, 57025, 8751
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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