Invitrogen™ ADAM15 Recombinant Rabbit Monoclonal Antibody (4T4X10)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA535694

Catalog No. PIMA535694

Description

Immunogen sequence: RHIRRRRDVV TETKTVELVI VADHSEAQKY RDFQHLLNRT LEVALLLDTF FRPLNVRVAL VGLEAWTQRD LVEISPNPAV TLENFLHWRR AHLLPRLPHD S.

The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.

Specifications

• Antigen: ADAM15
• Classification: Recombinant Monoclonal
• Concentration: 3 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O88839, Q13444, Q9QYV0
• Gene Symbols: Adam15
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 200-300 of human ADAM15 (Q13444).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: 4T4X10
• Conjugate: Unconjugated
• Gene: Adam15
• Gene Alias: a disintegrin and metallopeptidase domain 15 (metargidin); a disintegrin and metalloprotease domain 15 (metargidin); a disintegrin and metalloproteinase; a disintegrin and metalloproteinase domain 15; a disintegrin and metalloproteinase domain 15 (metargidin); AD56; ADAM; ADAM 15; ADAM metallopeptidase domain 15; Adam15; ADAMs; CRII-7; disintegrin and metalloprotease 15; disintegrin and metalloproteinase domain-containing protein 15; Mdc15; MDC-15; metalloendopeptidases; Metalloprotease RGD disintegrin protein; metalloproteinase-like, disintegrin-like, and cysteine-rich protein 15; metargidin; tMDC VI; tMDCVI
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11490, 57025, 8751
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid