Invitrogen™ ADAM22 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA587579

Catalog No. PIPA587579

Description

Immunogen sequence: SKRQLRRYPR NVEEETKYIE LMIVNDHLMF KKHRLSVVHT NTYAKSVVNM ADLIYKDQLK TRIVLVAMET WATDNKFAIS ENPLITLREF MKYRRDFIKE KSDAVHLFSG SQFESSRSGA AYIGGICSLL KGGGVNEFGK TDLMAVTLAQ SLAHNIGIIS DKRKLASGEC KCEDTWSG; Positive Samples: SH-SY5Y, Mouse brain, Mouse kidney, Mouse heart, Rat kidney, Rat heart; Cellular Location: Cell projection, Membrane, Single-pass type I membrane protein, axon.

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene is highly expressed in the brain and may function as an integrin ligand in the brain. Alternative splicing results in several transcript variants.

Specifications

• Antigen: ADAM22
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Adam22
• Gene Alias: 2900022I03Rik; a disintegrin and metallopeptidase domain 22; a disintegrin and metalloprotease domain (ADAM) 22; a disintegrin and metalloprotease domain 22; a disintegrin and metalloproteinase; a disintegrin and metalloproteinase domain 22; ADAM; ADAM 22; ADAM metallopeptidase domain 22; Adam22; ADAMs; AI854032; Disintegrin and metalloproteinase domain-containing protein 22; MDC2; metalloendopeptidases; Metalloproteinase-disintegrin ADAM22-3; metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2; MGC149832
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11496, 53616, 57033
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.76 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q9P0K1, Q9R1V6
• Gene Symbols: Adam22
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 223-400 of human ADAM22 (NP_0041851).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG