Invitrogen™ ADAMTS1 Polyclonal Antibody

Catalog No.	Quantity
PIPA532653	50 μg

Catalog No. PIPA532653 Supplier Invitrogen™ Supplier No. PA532653

Description

Rabbit Polyclonal Antibody

Percent identity with other species by BLAST analysis: Human, Gorilla (100%); Orangutan, Monkey, Marmoset (94%); Gibbon (88%). For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.

ADAMTS-1 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene contains two disintegrin loops and three C-terminal TS motifs and has anti-angiogenic activity. The expression of this gene may be associated with various inflammatory processes as well as development of cancer cachexia. This gene is likely to be necessary for normal growth, fertility, and organ morphology and function.

Specifications

• Antigen: ADAMTS1
• Applications: Immunohistochemistry (Paraffin)
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 0.1% sodium azide
• Gene: ADAMTS1
• Gene Accession No.: Q9UHI8
• Gene Alias: a disintegrin and metalloproteinase; A disintegrin and metalloproteinase with thrombospondin motifs 1; a disintegrin and metalloproteinase with thrombospondin motifs 1 (ADAMTS-1); a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1; a disintegrin-like and metallopeptidse (reprolysin type) with thrombospondin type 1 motif, 1; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 1; ADAM; ADAM metallopeptidase with thrombospondin type 1 motif 1; ADAM metallopeptidase with thrombospondin type 1 motif, 1; ADAMs; ADAMTS; ADAM-TS 1; Adamts1; ADAM-TS1; ADAMTS-1; C3-C5; human metalloproteinase with thrombospondin type 1 motifs; KIAA1346; metalloendopeptidases; METH1; METH-1
• Gene Symbols: ADAMTS1
• Host Species: Rabbit
• Immunogen: Synthetic 17 amino acid peptide from internal region of human ADAMTS1.
• Purification Method: Antigen Affinity Chromatography
• Quantity: 50 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 9510
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov