Invitrogen™ ADAMTS1 Polyclonal Antibody

Catalog No.	Quantity
PIPA547790	100 μg

Catalog No. PIPA547790 Supplier Invitrogen™ Supplier No. PA547790

Description

Sheep Polyclonal Antibody

In direct ELISAs, less than 5% cross-reactivity with recombinant human (rh) ADAMTS4 and rhADAMTS15 is observed and less than 1% cross-reactivity with rhADAMTSL1.2, rhADAMTSL2, rhADAMTS5, rhADAMTS8, rhADAMTS10, rhADAMTS12, rhADAMTS13, and rhADAMTS16 is observed. Reconstitute at 0.2 mg/mL in sterile PBS.

ADAMTS-1 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene contains two disintegrin loops and three C-terminal TS motifs and has anti-angiogenic activity. The expression of this gene may be associated with various inflammatory processes as well as development of cancer cachexia. This gene is likely to be necessary for normal growth, fertility, and organ morphology and function.

Specifications

• Antigen: ADAMTS1
• Applications: Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot
• Classification: Polyclonal
• Concentration: 0.2 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 5% trehalose and No Preservative
• Gene: ADAMTS1
• Gene Accession No.: P97857, Q9UHI8
• Gene Alias: a disintegrin and metalloproteinase; A disintegrin and metalloproteinase with thrombospondin motifs 1; a disintegrin and metalloproteinase with thrombospondin motifs 1 (ADAMTS-1); a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1; a disintegrin-like and metallopeptidse (reprolysin type) with thrombospondin type 1 motif, 1; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 1; ADAM; ADAM metallopeptidase with thrombospondin type 1 motif 1; ADAM metallopeptidase with thrombospondin type 1 motif, 1; ADAMs; ADAMTS; ADAM-TS 1; Adamts1; ADAM-TS1; ADAMTS-1; C3-C5; human metalloproteinase with thrombospondin type 1 motifs; KIAA1346; metalloendopeptidases; METH1; METH-1
• Gene Symbols: ADAMTS1
• Host Species: Sheep
• Immunogen: CHO-derived recombinant mouse ADAMTS1 Phe254-Cys725.
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 11504, 9510
• Target Species: Human, Mouse
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG