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Invitrogen™ ADAMTS13 Polyclonal Antibody
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Catalog No. PIPA5139814
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100 μL
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PIPA5139814 100 μL
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Catalog No. PIPA5139814 Supplier Invitrogen™ Supplier No. PA5139814
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Description

Rabbit Polyclonal Antibody

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user. Immunogen sequence: RYGSQLAPET FYRECDMQLF GPWGEIVSPS LSPATSNAGG CRLFINVAPH ARIAIHALAT NMGAGTEGAN ASYILIRDTH SLRTTAFHGQ QV Highest antigen sequence indentity to the following orthologs: Mouse - 71%, Rat - 64%.

ADAMTS13 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme is the von Willebrand Factor (vWF)-cleaving protease, which is responsible for cleaving at the site of Tyr842-Met843 of the vWF molecule. A deficiency of this enzyme is associated with thrombotic thrombocytopenic purpura.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ADAMTS13
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene ADAMTS13
Gene Accession No. Q76LX8
Gene Alias a disintegrin and metalloproteinase; A disintegrin and metalloproteinase with thrombospondin motifs 13; A disintegrin and metalloproteinase with thrombospondin motifs 13-like; a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 13; ADAM; ADAM metallopeptidase with thrombospondin type 1 motif 13; ADAM metallopeptidase with thrombospondin type 1 motif, 13; ADAMs; ADAM-TS 13; ADAMTS13; ADAM-TS13; ADAMTS-13; C9orf8; Gm710; LOC102554393; metalloendopeptidases; UNQ6102/PRO20085; von Willebrand factor-cleaving protease; vWF-cleaving protease; VWFCP; vWF-CP; vWF-CP mRNA for von Willebrand factor-cleaving
Gene Symbols ADAMTS13
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human ADAMTS13. Recombinant protein control fragment (Product #RP-108889).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11093
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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