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Invitrogen™ ADAMTS2 Polyclonal Antibody
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Catalog No. PIPA575602
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100 μL
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PIPA575602 100 μL
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Catalog No. PIPA575602 Supplier Invitrogen™ Supplier No. PA575602
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Description

Rabbit Polyclonal Antibody

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene excises the N-propeptide of type I, type II and type V procollagens. Mutations in this gene cause Ehlers-Danlos syndrome type VIIC, a recessively inherited connective-tissue disorder. Alternative splicing results in two transcript variants. The short transcript encodes a protein which has no significant procollagen N-peptidase activity.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ADAMTS2
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene Adamts2
Gene Accession No. O95450, Q8C9W3
Gene Alias a disintegrin and metalloproteinase; A disintegrin and metalloproteinase with thrombospondin motifs 2; a disintegrin and metalloproteinase with thrombospondin repeats; a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 2; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 2; ADAM; ADAM metallopeptidase with thrombospondin type 1 motif 2; ADAM metallopeptidase with thrombospondin type 1 motif, 2; ADAMs; ADAM-TS 2; ADAMTS2; ADAM-TS2; ADAMTS-2; ADAMTS-3; hPCPNI; metalloendopeptidases; mKIAA4060; NPI; PC I-NP; PCINP; PCI-NP; PCPNI; PNPI; Procollagen I N-proteinase; procollagen I/II amino propeptide-processing enzyme; Procollagen N-endopeptidase; procollagen N-proteinase; RGD1565950
Gene Symbols Adamts2
Host Species Rabbit
Immunogen Synthetic peptide corresponding to residues in Human ADAMTS2.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 216725, 287899, 9509
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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