Learn More
Invitrogen™ ADAMTS2 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA587766
Description
Positive Samples: A-375, U-87MG, THP-1, Rat thymus, ; Cellular Location: extracellular matrix, extracellular space Immunogen sequence: PRNISDPSKK SYVVQWLSRP DPDSPIRKIS SKGHCQGDKS IFCRMEVLSR YCSIPGYNKL CCKSCNLYNN LTNVEGRIEP PPGKHNDIDV FMPTLPVPTV AMEVRPSPST PLEVPLNASS TNATEDHPET NAVDEPYKIH GLEDEVQPPN LIPRRPSPYE KTRNQRIQEL IDEMRKKEML GKF.
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene excises the N-propeptide of type I, type II and type V procollagens. Mutations in this gene cause Ehlers-Danlos syndrome type VIIC, a recessively inherited connective-tissue disorder. Alternative splicing results in two transcript variants. The short transcript encodes a protein which has no significant procollagen N-peptidase activity.
Specifications
ADAMTS2 | |
Polyclonal | |
Unconjugated | |
Adamts2 | |
a disintegrin and metalloproteinase; A disintegrin and metalloproteinase with thrombospondin motifs 2; a disintegrin and metalloproteinase with thrombospondin repeats; a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 2; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 2; ADAM; ADAM metallopeptidase with thrombospondin type 1 motif 2; ADAM metallopeptidase with thrombospondin type 1 motif, 2; ADAMs; ADAM-TS 2; ADAMTS2; ADAM-TS2; ADAMTS-2; ADAMTS-3; hPCPNI; metalloendopeptidases; mKIAA4060; NPI; PC I-NP; PCINP; PCI-NP; PCPNI; PNPI; Procollagen I N-proteinase; procollagen I/II amino propeptide-processing enzyme; Procollagen N-endopeptidase; procollagen N-proteinase; RGD1565950 | |
Rabbit | |
Affinity Chromatography | |
RUO | |
287899, 9509 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
ELISA, Western Blot | |
2.88 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
O95450 | |
Adamts2 | |
Recombinant fusion protein containing a sequence corresponding to amino acids 1029-1213 of human ADAMTS2 (O95450). | |
100 μL | |
Primary | |
Human, Rat, Rat | |
Antibody | |
IgG |
Safety and Handling
Your input is important to us. Please complete this form to provide feedback related to the content on this product.