Invitrogen™ ADAMTS3 Polyclonal Antibody

Sheep Polyclonal Antibody

Supplier:  Invitrogen™ PA547744

Catalog No. PIPA547744

Description

In direct ELISAs and Western blots, approximately 3% cross-reactivity with recombinant human (rh) ADAMTS4 and less than 1% cross-reactivity with rhADAMTS1, rhADAMTS5, rhADAMTS13, and rhADAMTSL1.2 is observed. Reconstitute at 0.2 mg/mL in sterile PBS.

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene is the major procollagen II N-propeptidase. A deficiency of this protein may be responsible for dermatosparaxis, a genetic defect of connective tissues.

Specifications

• Antigen: ADAMTS3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ADAMTS3
• Gene Alias: a disintegrin and metalloproteinase; A disintegrin and metalloproteinase with thrombospondin motifs 3; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 3; ADAM; ADAM metallopeptidase with thrombospondin type 1 motif 3; ADAM metallopeptidase with thrombospondin type 1 motif, 3; ADAMs; ADAM-TS 3; ADAMTS3; ADAM-TS3; ADAMTS-3; ADAMTS-4; KIAA0366; metalloendopeptidases; PC II-NP; procollagen II amino propeptide-processing enzyme; Procollagen II N-proteinase; zinc metalloendopeptidase
• Host Species: Sheep
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9508
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunoprecipitation, Western Blot
• Concentration: 0.2 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: O15072
• Gene Symbols: ADAMTS3
• Immunogen: CHO-derived recombinant human ADAMTS3 Ser19-Cys712.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG