Invitrogen™ ADAMTS5 Recombinant Rabbit Monoclonal Antibody (1W9P3)

Catalog No.	Quantity
FEMA551523	100 μL

Catalog No. FEMA551523 Supplier Invitrogen™ Supplier No. MA551523

Description

Rabbit Recombinant Monoclonal Antibody

Immunogen sequence: NNGRYCTGKR AIYRSCSLMP CPPNGKSFRH EQCEAKNGYQ SDAKGVKTFV EWVPKYAGVL PADVCKLTCR AKGTGYYVVF SPKVTDGTEC RLYSNSVCVR.

ADAMTS5, also known as Implantin or Aggrecanase 2, is a member of the larger family of ADAMs (A Disintegrin And Metalloproteinase) metalloproteinases containing thrombospondin (TS) repeats. ADAMTS5 (A Disintegrin And Metalloproteinase with Thrombospondin-5 motif) was first described as ADAMTS5, a protein elevated in mice during the peri-implantion period. At the same time, another group identified Aggrecanase 11, a protein elevated in arthritic synovium. The name was later changed to ADAMTS5. ADAMTS5 is expressed in human and mouse. It has been found in heart, lung, cervix, uterus, ovary, brain, cartilage, and numerous other tissues, as well as chondroblastoma cell lines.

Specifications

• Antigen: ADAMTS5
• Applications: ELISA, Western Blot
• Classification: Recombinant Monoclonal
• Clone: 1W9P3
• Concentration: 1.55 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.09% sodium azide; pH 7.3
• Gene: ADAMTS5
• Gene Accession No.: Q9R001, Q9UNA0
• Gene Alias: 9530092O11Rik; a disintegrin and metalloproteinase; A disintegrin and metalloproteinase with thrombospondin motifs 11; A disintegrin and metalloproteinase with thrombospondin motifs 5; a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2); a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 5; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2); ADAM; ADAM metallopeptidase with thrombospondin type 1 motif 5; ADAM metallopeptidase with thrombospondin type 1 motif, 5; ADAMs; ADAM-TS 11; ADAM-TS 5; ADAMTS family member; ADAMTS1; ADAMTS11; ADAMTS-11; ADAMTS5; ADAM-TS5; ADAMTS-5; ADMP2; ADMP-2; Aggrecanase 2; Aggrecanase-2; AI481094; ASMP-2; Implantin; metalloendopeptidases
• Gene Symbols: ADAMTS5
• Host Species: Rabbit
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 601-700 of human ADAMTS5 (NP_008969.2).
• Purification Method: Affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 11096, 23794, 304135
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Format: Liquid
• Isotype: IgG