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Invitrogen™ ADAMTS8 Polyclonal Antibody
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Catalog No. PA551350
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100 μL
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PA551350 100 μL
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Catalog No. PA551350 Supplier Invitrogen™ Supplier No. PA551350
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Description

Rabbit Polyclonal Antibody

The antibody detects endogenous levels of total ADAMTS8 protein. Peptide sequence: THKYAPFIII GLHLALGIFS FTLDTWSTSR GDTAEILGSG AGIACGSHVT Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93% The antibody detects endogenous levels of total ADAMTS8 protein.

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains two C-terminal TS motifs, and disrupts angiogenesis in vivo. A number of disorders have been mapped in the vicinity of this gene, most notably lung neoplasms.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ADAMTS8
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 1.6 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene ADAMTS8
Gene Accession No. Q9UP79
Gene Alias a disintegrin and metalloproteinase; A disintegrin and metalloproteinase with thrombospondin motifs 8; a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 8; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 8; ADAM; ADAM metallopeptidase with thrombospondin type 1 motif 8; ADAM metallopeptidase with thrombospondin type 1 motif, 8; ADAMs; ADAM-TS 8; ADAMTS8; ADAM-TS8; ADAMTS-8; ADAMTS-8 precursor (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2); EC 3.4.24.14; EC 3.4.24.82; FLJ41712; metalloendopeptidases; METH2; METH-2; METH2ADAM-TS METH-8; METH-8
Gene Symbols ADAMTS8
Host Species Rabbit
Immunogen Synthetic peptide of human ADAMTS8.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11095
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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