Invitrogen™ ADAT3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA563626

Catalog No. PIPA563626

Description

Immunogen sequence: GAVRKLDADE DGLPYLCTGY DLYVTREPCA MCAMALVHAR ILRVFYGAPS PDGALGTRFR IHARPDLNHR FQVFRGVLEE QCRWLD Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 26%.

This gene encodes a subunit of a tRNA-specific adenosine deaminase. This heterodimeric enzyme converts adenosine to inosine in the tRNA anticodon. A mutation in this gene causes a syndrome characterized by intellectual disability and strabismus. This gene shares its 5' exon with the overlapping gene, secretory carrier membrane protein 4. ADAT3 (Adenosine Deaminase TRNA Specific 3) is a Protein Coding gene. Diseases associated with ADAT3 include Neurodevelopmental Disorder With Brain Abnormalities, Poor Growth, And Dysmorphic Facies and Cone-Rod Dystrophy 10. Among its related pathways are tRNA processing and Processing of Capped Intron-Containing Pre-mRNA. Gene Ontology (GO) annotations related to this gene include hydrolase activity. An important paralog of this gene is ADAT2.

Specifications

• Antigen: ADAT3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ADAT3
• Gene Alias: ADAT3; adenosine deaminase, tRNA specific 3; adenosine deaminase, tRNA-specific 3; adenosine deaminase, tRNA-specific 3, TAD3 homolog; FWP005; MRT36; MST121; MSTP121; Probable inactive tRNA-specific adenosine deaminase-like protein 3; S863-5; TAD3; tRNA-specific adenosine deaminase 3 homolog; tRNA-specific adenosine deaminase-like protein 3; tRNA-specific adenosine-34 deaminase subunit ADAT3
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 113179
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q96EY9
• Gene Symbols: ADAT3
• Immunogen: Recombinant protein corresponding to Human ADAT3. Recombinant protein control fragment (Product #RP-99241).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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