Invitrogen™ ADCY10 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA553633

Catalog No. PIPA553633

Description

Immunogen sequence: RNTTYIVIGA VQPNDISNKI CLDLNVSCIS KELDSYLGEG SCGIPFYCEE LLKNLEHHEV LVFQQTESEE KTNRTWNNLF KYSIKLTEKL NMVTLHSDKE SEEVCHLTSG VRLKNLSPPT SLKEISLI Highest antigen sequence identity to the following orthologs: Mouse - 64%, Rat - 67%.

SAC belongs to a distinct class of mammalian adenylyl cyclase that is soluble and insensitive to G protein or forskolin regulation. It is localized in the cytoplasm and is thought to function as a general bicarbonate sensor throughout the body. It may also play an important role in the generation of cAMP in spermatozoa, implying possible roles in sperm maturation through the epididymis, capacitation, hypermotility, and/or the acrosome reaction.The protein encoded by this gene belongs to a distinct class of mammalian adenylyl cyclase that is soluble and insensitive to G protein or forskolin regulation. It is localized in the cytoplasm and is thought to function as a general bicarbonate sensor throughout the body. It may also play an important role in the generation of cAMP in spermatozoa, implying possible roles in sperm maturation through the epididymis, capacitation, hypermotility, and/or the acrosome reaction. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Specifications

• Antigen: ADCY10
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ADCY10
• Gene Alias: 3',5'-cyclic AMP synthetase; 4930431D04Rik; 4931412F17; Adcy10; adenylate cyclase 10; adenylate cyclase 10 (soluble); adenylate cyclase 10, soluble; Adenylate cyclase homolog; Adenylate cyclase type 10; AH-related protein; ATP pyrophosphate-lyase; epididymis secretory sperm binding protein Li 7a; germ cell soluble adenylyl cyclase; HCA2; HEL-S-7a; hsAC; RP1-313L4.2; Sac; SACI; Sacy; soluble adenylyl cyclase; testicular soluble adenylyl cyclase; testicular soluble adenylyl cyclase (SAC)
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 55811
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q96PN6
• Gene Symbols: ADCY10
• Immunogen: Recombinant protein corresponding to Human ADCY10. Recombinant protein control fragment (Product #RP-90978).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG