Invitrogen™ ADCY6 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5118931

Catalog No. PIPA5118931

Description

ADCY6 Polyclonal Antibody for Western Blot, IHC (P)

This gene encodes a member of the adenylyl cyclase family of proteins, which are required for the synthesis of cyclic AMP. All members of this family have an intracellular N-terminus, a tandem repeat of six transmembrane domains separated by a cytoplasmic loop, and a C-terminal cytoplasmic domain. The two cytoplasmic regions bind ATP and form the catalytic core of the protein. Adenylyl cyclases are important effectors of transmembrane signaling pathways and are regulated by the activity of G protein coupled receptor signaling. This protein belongs to a small subclass of adenylyl cyclase proteins that are functionally related and are inhibited by protein kinase A, calcium ions and nitric oxide. A mutation in this gene is associated with arthrogryposis multiplex congenita.

Specifications

• Antigen: ADCY6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ADCY6
• Gene Alias: AC6; ACVI; Adcy6; ADCYB; adenylate cyclase 6; adenylate cyclase type 6; Adenylate cyclase type VI; adenylyl cyclase 6; ATP pyrophosphate-lyase 6; ca(2+)-inhibitable adenylyl cyclase; DKFZp779F075; KIAA0422; LCCS8; mKIAA0422
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 112, 11512
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4
• Gene Accession No.: O43306, Q01341
• Gene Symbols: ADCY6
• Immunogen: Recombinant protein Adenylate Cyclase 6. The antigen corresponds to amino acid range 314-501 of the target protein.
• Quantity: 200 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG