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Adenomatous Polyposis Coli Rabbit anti-Human, Polyclonal, Bioss
SDP

Rabbit Polyclonal Antibody

Supplier:  Bioss BS3680R

Encompass_Preferred

Catalog No. 50-198-5577


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Description

Description

This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.
Specifications

Specifications

Adenomatous Polyposis Coli
Polyclonal
Unconjugated
Apc
adenomatosis polyposis coli; adenomatosis polyposis coli tumor suppressor; adenomatous polyposis coli; Adenomatous polyposis coli protein; AI047805; APC; APC, WNT signaling pathway regulator; AU020952; AW124434; BTPS2; CC1; Deleted in polyposis 2.5; DP2; DP2.5; DP3; FAP; FPC; GS; mAPC; Min; multiple intestinal neoplasia; PPP1R46; Protein APC; protein phosphatase 1, regulatory subunit 46; RATAPC; truncated adenomatosis polyposis coli; WNT signaling pathway regulator
Rabbit
Protein A
RUO
324
-20°C
Liquid
Immunofluorescence, Immunohistochemistry (Paraffin)
1 μg/mL
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
P25054
Apc
KLH conjugated synthetic peptide derived from human APC.
100 μL
Primary
Human
Antibody
IgG
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