Invitrogen™ Adenovirus Polyclonal Antibody

Catalog No.	Quantity
PA17201	1 mL

Catalog No. PA17201 Supplier Invitrogen™ Supplier No. PA17201

Description

Goat Polyclonal Antibody

PA1-7201 detect the adenovirus. This antibody does not cross-react with parainfluenza 1-3, Influenza. A & B, RSV, hMPV, and Rhinovirus (type 16). PA1-7201 has been successfully used in immunofluorescence and ELISA procedures. PA1-7201 immunogen is gradient purified, disrupted Adenovirus type 5 virions. Store at 4ºC for 6 months. For extended storage, store at -20ºC.

Adenoviruses are DNA viruses generally widespread in nature that are frequently the cause of acute upper respiratory tract infections (i.e. common colds). 49 human adenovirus serotypes have been discovered and divided into six subgroups, A to E, based on observation. They are an important cause of respiratory illness, conjunctivitis, gastroenteritis, and have more recently been recognized as a potential cause of sexually transmitted diseases. Several types have oncogenic potential though most cause self-limiting febrile illnesses characterized by inflammation of conjunctivae and the respiratory tract. The virus can be isolated from the majority of tonsils/adenoids surgically removed, indicating latent infections. It is not known how long the virus can persist in the body, or whether it is capable of reactivation after long periods. In patients experiencing immunosuppression (e.g. AIDS) it can be reactivated, causing disease. Adenovirus vectors, particularly those based on Ad5, have shown great promise for the development of gene therapy protocols and have been used for clinical purpose. Adenoviruses capsids have three principal protein components: the hexon, the penton, and the fiber. Hexon protein is a major coat protein (240 hexons per particle). Each hexon capsomere is homotrimer of the hexon protein, a complex protein of over 900 residues.

Specifications

• Antigen: Adenovirus
• Applications: ELISA, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 5.0 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 0.1% sodium azide; pH 7.2
• Gene Alias: Adeno Virus; AdV; HADV
• Host Species: Goat
• Immunogen: Gradient purified, disrupted Adenovirus type 5 virions.
• Purification Method: IgG Fraction
• Quantity: 1 mL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Virus
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG