Invitrogen™ Adenylate Cyclase 5/6 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA577847

Catalog No. PIPA577847

Description

Positive Control: U87-MG, SK-N-SH Predicted Reactivity: Mouse (100%), Rat (100%), Zebrafish (98%), Dog (100%), Rabbit (100%), Chicken (97%), Bovine (100%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Adenylate cyclase 5/6 encodes a member of the membrane-bound adenylyl cyclase enzymes. Adenylyl cyclases mediate G protein-coupled receptor signaling through the synthesis of the second messenger cAMP. Activity of the encoded protein is stimulated by the Gs alpha subunit of G protein-coupled receptors and is inhibited by protein kinase A, calcium and Gi alpha subunits. Single nucleotide polymorphisms in this gene may be associated with low birth weight and type 2 diabetes. Alternatively spliced transcript variants that encode different isoforms have been observed for this gene.

Specifications

• Antigen: Adenylate Cyclase 5/6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ADCY6
• Gene Alias: A cyclase V; A cyclase VI; AC5; AC6; ACVI; Adcy5; Adcy6; ADCYB; adenylate cyclase 5; adenylate cyclase 6; adenylate cyclase type 5; Adenylate cyclase type 6; adenylate cyclase type V; Adenylate cyclase type VI; adenylyl cyclase 5; Adenylyl cyclase 6; adenylyl cyclase type V; ATP pyrophosphate-lyase 5; ATP pyrophosphate-lyase 6; AW121902; ca(2+)-inhibitable adenylyl cyclase; FDFM; KIAA0422; LCCS8; mKIAA0422
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 111, 112, 11512, 224129
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 6.45 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: O43306, O95622, P84309, Q01341
• Gene Symbols: ADCY5, ADCY6
• Immunogen: Recombinant protein encompassing a sequence within the center region of mouse Adenylate Cyclase 5. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG