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Invitrogen™ Adenylate Kinase 1 Polyclonal Antibody
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Catalog No. PIPA589246
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100 μL
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Catalog No. Quantity
PIPA589246 100 μL
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Catalog No. PIPA589246 Supplier Invitrogen™ Supplier No. PA589246
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MEEKLKKTKI IFVVGGPGSG KGTQCEKIVQ KYGYTHLSTG DLLRSEVSSG SARGKKLSEI MEKGQLVPLE TVLDMLRDAM VAKVNTSKGF LIDGYPREVQ QGEEFERRIG QPTLLLYVDA GPETMTQRLL KRGETSGRVD DNEETIKKRL ETYYKATEPV IAFYEKRGIV RKVNAEGSVD SVFSQVCTHL DALK; Positive Samples: Mouse heart, Mouse skeletal muscle; Cellular Location: Cytoplasm.

Adenylate kinase is an enzyme involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate group among adinine nucleotides. Three isozymes of adenylate kinase have been identified in vertebrates, adenylate isozyme 1 (AK1), 2 (AK2) and 3 (AK3). AK1 is found in the cytosol of skeletal muscle, brain and erythrocytes, whereas AK2 and AK3 are found in the mitochondria of other tissues including liver and heart. AK1 was identified because of its association with a rare genetic disorder causing nonspherocytic hemolytic anemia where a mutation in the AK1 gene was found to reduce the catalytic activity of the enzyme.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Adenylate Kinase 1
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.21 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene AK1
Gene Accession No. P00568, P39069, Q9R0Y5
Gene Alias adenylate kinase 1; adenylate kinase isoenzyme 1; adenylate kinase isoenzyme 1 {ECO:0000255; Adenylate monophosphate kinase; adenylate monophosphate kinase {ECO:0000255; AK 1; AK 1 {ECO:0000255; Ak1; Ak-1; ATP:AMP phosphotransferase; ATP:AMP phosphotransferase {ECO:0000255; ATP-AMP transphosphorylase 1; ATP-AMP transphosphorylase 1 {ECO:0000255; B430205N08Rik; cytosolic adenylate kinase; HAMAP-Rule:MF_03171}; HTL-S-58j; I79_014777; Myokinase; myokinase {ECO:0000255; testis secretory sperm binding protein Li 58j
Gene Symbols AK1
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-194 of human AK1 (NP_0004671).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11636, 203, 24183
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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