Invitrogen™ Adenylate Kinase 2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA528611

Catalog No. PIPA528611

Description

Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji, mouse brain. Predicted reactivity: Mouse (95%), Rat (94%), Zebrafish (81%), Xenopus laevis (82%), Rhesus Monkey (100%), Bovine (94%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Adenylate kinases are involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. Three isozymes of adenylate kinase, namely 1, 2, and 3, have been identified in vertebrates; this gene encodes isozyme 2. Expression of these isozymes is tissue-specific and developmentally regulated. Isozyme 2 is localized in the mitochondrial intermembrane space and may play a role in apoptosis. Two transcript variants encoding distinct isoforms have been identified for this gene.

Specifications

• Antigen: Adenylate Kinase 2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: AK2
• Gene Alias: adenylate kinase 2; adenylate kinase 2, mitochondrial; adenylate kinase 2, mitochondrial {ECO:0000255; Adenylate kinase 2, mitochondrial, N-terminally processed; adenylate kinase isoenzyme 2, mitochondrial; adenylate monophosphate kinase; adenylate monophosphate kinase {ECO:0000255; ADK2; AK 2; AK 2 {ECO:0000255; Ak2; Ak-2; ATP:AMP phosphotransferase; ATP:AMP phosphotransferase {ECO:0000255; ATP-AMP transphosphorylase 2; ATP-AMP transphosphorylase 2 {ECO:0000255; D4Ertd220e; HAMAP-Rule:MF_03168}; si:ch211-197n10.1; testis secretory sperm-binding protein Li 220n; wu:fb34f05; wu:fj80e03
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11637, 204, 24184
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.35 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P29410, P54819, Q9WTP6
• Gene Symbols: AK2
• Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 239 of Human Adenylate kinase 2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG