Adenylosuccinate Lyase Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-7216	100 μL

Catalog No. 50-198-7216 Supplier Bioss Supplier No. BS6352R

Description

Rabbit Polyclonal Antibody

ADSL (adenylosuccinate lyase), also known as AMPS, ASL or ASASE, is a 484 amino acid protein that is involved in both purine biosynthesis and in the formation of adenosine monophosphate (AMP) from inosine monophosphate. Expressed ubiquitously, ADSL catalyzes two key reactions in AMP biosynthesis, namely the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and the subsequent removal of fumarate from adenylosuccinate to yield AMP. Defects in the gene encoding ADSL are the cause of adenylosuccinase deficiency (ADSL deficiency), an autosomal recessive disorder characterized by epilepsy, growth retardation and muscular wasting. Multiple isoforms of ADSL exist due to alternative splicing events.

Specifications

• Antigen: Adenylosuccinate Lyase
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: Adsl
• Gene Accession No.: P30566
• Gene Alias: Adenylosuccinase; Adenylosuccinate lyase; adenylosuccinate lyase 1; Adl; ADSL; AMPS; ASase; ASL; LOC101864843; null; test; uncharacterized LOC101864843; uncharacterized protein LOC101864843
• Gene Symbols: Adsl
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide derived from human Adenylosuccinate Lyase.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 158
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG