Invitrogen™ ADFP Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5118879

Catalog No. PIPA5118879

Description

Antibody detects endogenous levels of total ADFP.

Milk lipid globules from humans, cows and rats contain a protein identified as adipocyte differentiation-related protein (ADFP). It is associated with the globule surface membrane material. This protein, previously believed to be specific to adipocytes, is a major constituent of the globule surface and is present in a detergent-insoluble complex that contains butyrophilin and xanthine oxidase. ADFP (Adipophilin) is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells. In tissues, however, expression of adipophilin is restricted to specific cell types, such as lactating mammary epithelial cells, adrenal cortex cells, Sertoli and Leydig cells of the male reproductive system, and steatosis or fatty change hepatocytes in alcoholic liver cirrhosis. ADFP may be a possible new marker for the identification of specialized differentiated cells containing lipid droplets and for diseases associated with fat-accumulating cells.

Specifications

• Antigen: ADFP
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Plin2
• Gene Alias: AA407157; Adfp; Adipophilin; adipose differentiation related protein; adipose differentiation-related protein; ADPH; Adrp; ADRP antibody; MGC10598; perilipin 2; perilipin-2; Plin2
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11520, 123, 298199
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P43883, Q99541
• Gene Symbols: Plin2
• Immunogen: A synthesized peptide derived from human PLIN2(Accession Q99541), corresponding to amino acid residues V267-L317.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG