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Invitrogen™ ADFP Polyclonal Antibody
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Catalog No. PIPA5120981
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100 μL
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PIPA5120981 100 μL
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Catalog No. PIPA5120981 Supplier Invitrogen™ Supplier No. PA5120981
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Description

Rabbit Polyclonal Antibody

Positive test controls include: HepG2, NIH/3T3, Mouse brain, Rat heart. The target is usually found in the following locations: Membrane, Peripheral membrane protein. Immunogen sequence: MMQLVSSGVE NALTKSELLV EQYLPLTEEE LEKEAKKVEG FDLVQKPSYY VRLGSLSTKL HSRAYQQALS RVKEAKQKSQ QTISQLHSTV HLIEFARKNV YSANQKIQDA QDKLYLSWVE WKRSIGYDDT DESHCAEHIE SRTLAIARNL TQQLQTTCHT LLSNIQGVPQ NIQDQAKHMG VMAGDIYSVF RNAASFKEVS DSLLTSSKGQ LQKMKESLDD VMDYLVNNTP LNWLVGPFYP QLTESQNAQD QGAEMDKSSQ ETQRSEHKTH.

Milk lipid globules from humans, cows and rats contain a protein identified as adipocyte differentiation-related protein (ADFP). It is associated with the globule surface membrane material. This protein, previously believed to be specific to adipocytes, is a major constituent of the globule surface and is present in a detergent-insoluble complex that contains butyrophilin and xanthine oxidase. ADFP (Adipophilin) is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells. In tissues, however, expression of adipophilin is restricted to specific cell types, such as lactating mammary epithelial cells, adrenal cortex cells, Sertoli and Leydig cells of the male reproductive system, and steatosis or fatty change hepatocytes in alcoholic liver cirrhosis. ADFP may be a possible new marker for the identification of specialized differentiated cells containing lipid droplets and for diseases associated with fat-accumulating cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ADFP
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.54 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Plin2
Gene Accession No. P43883, Q99541
Gene Alias AA407157; Adfp; Adipophilin; adipose differentiation related protein; adipose differentiation-related protein; ADPH; Adrp; ADRP antibody; MGC10598; perilipin 2; perilipin-2; Plin2
Gene Symbols Plin2
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 168-437 of human Perilipin-2 (NP_0011132).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11520, 123, 298199
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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