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Invitrogen™ ADH5 Polyclonal Antibody
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Catalog No. PIPA589245
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100 μL
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PIPA589245 100 μL
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Catalog No. PIPA589245 Supplier Invitrogen™ Supplier No. PA589245
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MANEVIKCKA AVAWEAGKPL SIEEIEVAPP KAHEVRIKII ATAVCHTDAY TLSGADPEGC FPVILGHEGA GIVESVGEGV TKLKAGDTVI PLYIPQCGEC KFCLNPKTNL CQKIRVTQGK GLMPDGTSRF TCKGKTILHY MGTSTFSEYT VVADISVAKI DPLAPLDKVC LLGCGISTGY GAAVNTAKLE PGSVCAVFGL GGVGLAVIMG CKVAGASRII GVDINKDKFA RAKEFGATEC INPQDFSKPI QEVLIEMTDG GVDYSFECIG NVKVMRAALE ACHKGWGVSV VVGVAASGEE IATRPFQLVT GRTWKGTAFG GWKSVESVPK LVSEYMSKKI KVDEFVTHNL SFDEINKAFE LMHSGKSIRT VVKI; Positive Samples: U-251MG; Cellular Location: Cytoplasm.

This gene encodes a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The encoded protein forms a homodimer. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde, a potent irritant and sensitizing agent that causes lacrymation, rhinitis, pharyngitis, and contact dermatitis. The human genome contains several non-transcribed pseudogenes related to this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ADH5
Applications ELISA, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.32 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene ADH5
Gene Accession No. P11766, P12711, P28474
Gene Alias ADH1C; Adh2; Adh-2; ADH3; ADH-3; ADH5; Adh-5; ADH-B2; ADHX; alcohol dehydrogenase (class III), chi polypeptide; alcohol dehydrogenase 1C (class I), gamma polypeptide; alcohol dehydrogenase 2; Alcohol dehydrogenase 5; alcohol dehydrogenase 5 (class III), chi polypeptide; alcohol dehydrogenase B2; Alcohol dehydrogenase class chi chain; alcohol dehydrogenase class-3; Alcohol dehydrogenase class-III; class III alcohol dehydrogenase; class III alcohol dehydrogenase, chi subunit; epididymis secretory sperm binding protein Li 60p; FALDH; FDH; formaldehyde dehydrogenase; glutathione-dependent formaldehyde dehydrogenase; GSH-FDH; GSNOR; HEL-S-60p; S-(hydroxymethyl)glutathione dehydrogenase; S-nitrosoglutathione reductase
Gene Symbols ADH5
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-374 of human ADH5/GSNOR (NP_0006623).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100145871, 11532, 128
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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