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Invitrogen™ Adiponectin Monoclonal Antibody (19F1)
Mouse Monoclonal Antibody
Supplier: Invitrogen™ MA1054
Description
MA1-054 detects adiponectin from human, rabbit and mouse samples. MA1-054 has been used successfully in Western blot, immunofluorescence, and ELISA procedures. By Western blot this antibody detects ~30 kDa protein representing Adiponectin in 3T3-L1 adipocytes. Immunofluorescence and ELISA of Adiponectin can also be performed using MA1-054. The MA1-054 immunogen is full length, recombinant, human adiponectin.
Adiponectin is a protein hormone secreted exclusively by adipocytes that regulates the metabolism of lipids and glucose. Adiponectin has been shown to play a role in various physiological processes including homeostasis and obesity. Decreased levels of adiponectin are associated with obese individuals as well as insulin resistance and hyperinsulinemia (type 2 diabetes). In mice adiponectin has been shown to improve insulin signaling, thus ameliorating insulin resistance. Through activation of AMP kinase and PPAR-alpha, adiponectin can increase fatty acid transport, oxidation, and dissipation in skeletal muscle, leading to a reduction of intramyocellular lipid levels and thus improved insulin signaling.
Specifications
Adiponectin | |
Monoclonal | |
1 mg/mL | |
PBS with 1mg/mL BSA and 0.05% sodium azide | |
Q15848, Q60994 | |
ADIPOQ | |
Full length, recombinant, human adiponectin. | |
100 μg | |
Primary | |
Human, Mouse, Rabbit | |
Antibody | |
IgG |
ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
19F1 | |
Unconjugated | |
ADIPOQ | |
30 kDa adipocyte complement-related protein; 30kDa; Acdc; Acrp30; Ad; adipo; adipocyte complement related protein; adipocyte complement related protein of 30 kDa; adipocyte complement-related 30 kDa protein; adipocyte complement-related protein of 30 kDa; adipocyte, C1Q and collagen domain containing; adipocyte, C1q and collagen domain-containing protein; Adipocyte-specific protein AdipoQ; adiponectin; adiponectin, C1Q and collagen domain containing; Adipoq; Adipose most abundant gene transcript 1 protein; adipose specific collagen-like factor; ADIPQTL1; ADPIOQ; ADPN; Apm1; APM-1; APN; GBP28; Gelatin-binding protein; gelatin-binding protein 28 | |
Mouse | |
Protein G | |
RUO | |
100009027, 11450, 9370 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
Safety and Handling
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