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Invitrogen™ Adiponectin Polyclonal Antibody
Goat Polyclonal Antibody
Supplier: Invitrogen™ PA548026
Description
In Western blots, approximately 45% cross-reactivity with recombinant mouse Adiponectin is observed and 35% cross-reactivity with recombinant human Adiponectin is observed. Reconstitute at 0.2 mg/mL in sterile PBS.
Adiponectin is a protein hormone secreted exclusively by adipocytes that regulates the metabolism of lipids and glucose. Adiponectin has been shown to play a role in various physiological processes including homeostasis and obesity. Decreased levels of adiponectin are associated with obese individuals as well as insulin resistance and hyperinsulinemia (type 2 diabetes). In mice adiponectin has been shown to improve insulin signaling, thus ameliorating insulin resistance. Through activation of AMP kinase and PPAR-alpha, adiponectin can increase fatty acid transport, oxidation, and dissipation in skeletal muscle, leading to a reduction of intramyocellular lipid levels and thus improved insulin signaling.
Specifications
Adiponectin | |
Polyclonal | |
Unconjugated | |
ADIPOQ | |
30 kDa adipocyte complement-related protein; 30kDa; Acdc; Acrp30; Ad; adipo; adipocyte complement related protein; adipocyte complement related protein of 30 kDa; adipocyte complement-related 30 kDa protein; adipocyte complement-related protein of 30 kDa; adipocyte, C1Q and collagen domain containing; adipocyte, C1q and collagen domain-containing protein; Adipocyte-specific protein AdipoQ; adiponectin; adiponectin, C1Q and collagen domain containing; Adipoq; Adipose most abundant gene transcript 1 protein; adipose specific collagen-like factor; ADIPQTL1; ADPIOQ; ADPN; Apm1; APM-1; APN; GBP28; Gelatin-binding protein; gelatin-binding protein 28 | |
Goat | |
Antigen affinity chromatography | |
RUO | |
246253 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Lyophilized |
Immunohistochemistry (Frozen), Western Blot, Immunocytochemistry | |
0.2 mg/mL | |
PBS with 5% trehalose and No Preservative | |
0 | |
ADIPOQ | |
Mouse myeloma cell line NS0-derived recombinant rat Adiponectin/Acrp30 Ile19-Asn244. | |
100 μg | |
Primary | |
Rat | |
Antibody | |
IgG |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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