ADM Monoclonal Antibody (OTI2A4), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA807045

Catalog No. 50-168-1374

Description

Adrenomedullin (ADM), a vasodilator produced by most contractile cells, is characterized by persistent hypotensive activity. ADM is involved in the regulation of fluid and electrolyte homeostasis and in the maintece of cardiovascular functioning. In hypertensive patients, the level of ADM in plasma is upregulated. Natriuresis is a common systemic manifestation of aneurysmal subarachnoid hemorrhage. ADM has strong natriuretic actions. ADM-induced natriuresis is caused by an increase in glomerular filtration rate and a decrease in distal tubular sodium reabsorption. ADM is present both in the periphery and brain, and can exert central effects such as decreasing food ingestion.

Specifications

• Antigen: ADM
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P35318
• Gene Symbols: ADM
• Immunogen: Human recombit protein fragment corresponding to amino acids 22-146 of human ADM produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot
• Clone: OTI2A4
• Conjugate: Unconjugated
• Gene: ADM
• Gene Alias: AM, PAMP
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 133
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid