ADM Mouse anti-Human, Clone: OTI2A4, lyophilized, TrueMAB™

Catalog No.	Quantity
50-166-8096	100 μg

Catalog No. 50-166-8096 Supplier OriGene Supplier No. CF807045

Description

Mouse Monoclonal Antibody

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Adrenomedullin (ADM), a vasodilator produced by most contractile cells, is characterized by persistent hypotensive activity. ADM is involved in the regulation of fluid and electrolyte homeostasis and in the maintece of cardiovascular functioning. In hypertensive patients, the level of ADM in plasma is upregulated. Natriuresis is a common systemic manifestation of aneurysmal subarachnoid hemorrhage. ADM has strong natriuretic actions. ADM-induced natriuresis is caused by an increase in glomerular filtration rate and a decrease in distal tubular sodium reabsorption. ADM is present both in the periphery and brain, and can exert central effects such as decreasing food ingestion.

Specifications

• Antigen: ADM
• Applications: Western Blot
• Classification: Monoclonal
• Clone: OTI2A4
• Conjugate: Unconjugated
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene: ADM
• Gene Accession No.: P35318
• Gene Alias: AM, PAMP
• Gene Symbols: ADM
• Host Species: Mouse
• Immunogen: Human recombit protein fragment corresponding to amino acids 22-146 of human ADM produced in E.coli.
• Purification Method: Affinity Chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 133
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG1