Invitrogen™ ADORA3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA536350

Catalog No. PIPA536350

Description

This antibody detects endogenous protein at a molecular weight of 38 kDa. Purity is >95% by SDS-PAGE.

Adenosine is involved in a variety of processes, including the synthesis of urea, the anti-inflammatory response and the inhibition of protein synthesis The adenosine receptors, including adenosine A1-R, adenosine A2A-R, adenosine A2B-R and adenosine A3-R, are integral membrane proteins that are members of the G protein-coupled receptor family. The A1-R protein mediates ureagenesis in a partially calcium-dependent manner. Adenosine is known to mediate coronary vasodilation via the A2A-R receptor. Collagen synthesis and total protein synthesis are inhibited in certain cells by adenosine, acting via the A2B receptors. Activation of the A3-R receptor inhibits the induction of the cytokine TNF alpha and blocks the endotoxin CD14 receptor signal transduction pathway.

Specifications

• Antigen: ADORA3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ADORA3
• Gene Alias: A3 adenosine receptor; A3AR; A3R; AA3R; AD026; adenosine A3 receptor; Adenosine A3-R; adenosine receptor A3; adenosine-3 receptor; Adora3; Agtrl1; angiotensin II receptor-like 1; angiotensin receptor-like 1; Apelin receptor; Apj; APJ (apelin) receptor; APJ receptor; APJR; Aplnr; ARA3; B78; BA552M11.5; G protein-coupled receptor; G protein-coupled receptor APJ; Gpcr2; GPCR34; G-protein coupled receptor 2; G-protein coupled receptor APJ; G-protein coupled receptor HG11; HG11; HG11 orphan receptor; MSR; msr/apj; RP11-552M11.7; TGPCR1
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11542, 140, 25370
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P0DMS8, P28647, Q61618
• Gene Symbols: ADORA3
• Immunogen: Synthetic peptide corresponding to amino acids C-terminus of human ADORA3.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG