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Invitrogen™ Adrenomedullin Monoclonal Antibody (C1), Invitrogen™
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Catalog No. PIMA543983
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20 μL
100 μL
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PIMA543983 100 μL
PIMA543984 20 μL
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Catalog No. PIMA543983 Supplier Invitrogen™ Supplier No. MA543983
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Mouse Monoclonal Antibody

Adrenomedullin (ADM), a vasodilator produced by most contractile cells, is characterized by persistent hypotensive activity. ADM is involved in the regulation of fluid and electrolyte homeostasis and in the maintenance of cardiovascular functioning. In hypertensive patients, the level of ADM in plasma is upregulated. Natriuresis is a common systemic manifestation of aneurysmal subarachnoid hemorrhage. ADM has strong natriuretic actions. ADM-induced natriuresis is caused by an increase in glomerular filtration rate and a decrease in distal tubular sodium reabsorption. ADM is present both in the periphery and brain, and can exert central effects such as decreasing food ingestion.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Adrenomedullin
Applications Western Blot
Classification Monoclonal
Clone C1
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4
Gene ADM
Gene Accession No. P35318
Gene Alias ADM; Adrenomedullin; AM; AMpreproadrenomedullin; Ap; H39316; PAMP; preproadrenomedullin; proadrenomedullin N-20 terminal peptide; ProAM N-terminal 20 peptide; ProAM-N20; RATAP
Gene Symbols ADM
Host Species Mouse
Immunogen Ala22-Gly147 (Accession P35318), with N-terminal His Tag.
Purification Method Protein A/G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 133
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2a κ
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