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Invitrogen™ Adrenomedullin Monoclonal Antibody (OTI8A1)
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Catalog No. PIMA526819
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100 μL
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Catalog No. Quantity
PIMA526819 100 μL
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Catalog No. PIMA526819 Supplier Invitrogen™ Supplier No. MA526819
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Description

Mouse Monoclonal Antibody

Adrenomedullin Monoclonal Antibody for IHC (P)

Adrenomedullin (ADM), a vasodilator produced by most contractile cells, is characterized by persistent hypotensive activity. ADM is involved in the regulation of fluid and electrolyte homeostasis and in the maintenance of cardiovascular functioning. In hypertensive patients, the level of ADM in plasma is upregulated. Natriuresis is a common systemic manifestation of aneurysmal subarachnoid hemorrhage. ADM has strong natriuretic actions. ADM-induced natriuresis is caused by an increase in glomerular filtration rate and a decrease in distal tubular sodium reabsorption. ADM is present both in the periphery and brain, and can exert central effects such as decreasing food ingestion.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Adrenomedullin
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone OTI8A1
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene ADM
Gene Accession No. P35318
Gene Alias ADM; Adrenomedullin; AM; AMpreproadrenomedullin; Ap; H39316; PAMP; preproadrenomedullin; proadrenomedullin N-20 terminal peptide; ProAM N-terminal 20 peptide; ProAM-N20; RATAP
Gene Symbols ADM
Host Species Mouse
Immunogen Human recombinant protein fragment corresponding to amino acids 22-146 of ADM produced in E.coli.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 133
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2b
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