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Invitrogen™ Adrenomedullin Polyclonal Antibody
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Catalog No. PIPA5103107
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100 μL
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PIPA5103107 100 μL
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Catalog No. PIPA5103107 Supplier Invitrogen™ Supplier No. PA5103107
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total ADM.

Adrenomedullin (ADM), a vasodilator produced by most contractile cells, is characterized by persistent hypotensive activity. ADM is involved in the regulation of fluid and electrolyte homeostasis and in the maintenance of cardiovascular functioning. In hypertensive patients, the level of ADM in plasma is upregulated. Natriuresis is a common systemic manifestation of aneurysmal subarachnoid hemorrhage. ADM has strong natriuretic actions. ADM-induced natriuresis is caused by an increase in glomerular filtration rate and a decrease in distal tubular sodium reabsorption. ADM is present both in the periphery and brain, and can exert central effects such as decreasing food ingestion.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Adrenomedullin
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene ADM
Gene Accession No. P35318, P43145, P97297
Gene Alias ADM; Adrenomedullin; AM; AMpreproadrenomedullin; Ap; H39316; PAMP; preproadrenomedullin; proadrenomedullin N-20 terminal peptide; ProAM N-terminal 20 peptide; ProAM-N20; RATAP
Gene Symbols ADM
Host Species Rabbit
Immunogen A synthesized peptide derived from human ADM(Accession P35318), corresponding to amino acid residues G12-G62.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11535, 133, 25026
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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