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Invitrogen™ Adrenomedullin Polyclonal Antibody
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Catalog No. PIPA536524
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100 μL
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PIPA536524 100 μL
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Catalog No. PIPA536524 Supplier Invitrogen™ Supplier No. PA536524
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Rabbit Polyclonal Antibody

Purity is >95% by SDS-PAGE.

Adrenomedullin (ADM), a vasodilator produced by most contractile cells, is characterized by persistent hypotensive activity. ADM is involved in the regulation of fluid and electrolyte homeostasis and in the maintenance of cardiovascular functioning. In hypertensive patients, the level of ADM in plasma is upregulated. Natriuresis is a common systemic manifestation of aneurysmal subarachnoid hemorrhage. ADM has strong natriuretic actions. ADM-induced natriuresis is caused by an increase in glomerular filtration rate and a decrease in distal tubular sodium reabsorption. ADM is present both in the periphery and brain, and can exert central effects such as decreasing food ingestion.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Adrenomedullin
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene ADM
Gene Accession No. P35318, P43145, P97297
Gene Alias ADM; Adrenomedullin; AM; AMpreproadrenomedullin; Ap; H39316; PAMP; preproadrenomedullin; proadrenomedullin N-20 terminal peptide; ProAM N-terminal 20 peptide; ProAM-N20; RATAP
Gene Symbols ADM
Host Species Rabbit
Immunogen Synthetic peptide corresponding to amino acids 70-120 of human ADM.
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11535, 133, 25026
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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