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Invitrogen™ Adrenomedullin Polyclonal Antibody
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Catalog No. PIPA5140125
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100 μL
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PIPA5140125 100 μL
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Catalog No. PIPA5140125 Supplier Invitrogen™ Supplier No. PA5140125
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Description

Rabbit Polyclonal Antibody

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user. Immunogen sequence: ADTARLDVAS EFRKKWNKWA LSRGKRELRM SSSYPTGLAD VKAGPAQTLI RPQDMKGASR S Highest antigen sequence indentity to the following orthologs: Rat - 64%, Mouse - 61%.

Adrenomedullin (ADM), a vasodilator produced by most contractile cells, is characterized by persistent hypotensive activity. ADM is involved in the regulation of fluid and electrolyte homeostasis and in the maintenance of cardiovascular functioning. In hypertensive patients, the level of ADM in plasma is upregulated. Natriuresis is a common systemic manifestation of aneurysmal subarachnoid hemorrhage. ADM has strong natriuretic actions. ADM-induced natriuresis is caused by an increase in glomerular filtration rate and a decrease in distal tubular sodium reabsorption. ADM is present both in the periphery and brain, and can exert central effects such as decreasing food ingestion.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Adrenomedullin
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene ADM
Gene Accession No. P35318
Gene Alias ADM; Adrenomedullin; AM; AMpreproadrenomedullin; Ap; H39316; PAMP; preproadrenomedullin; proadrenomedullin N-20 terminal peptide; ProAM N-terminal 20 peptide; ProAM-N20; RATAP
Gene Symbols ADM
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human ADM. Recombinant protein control fragment (Product #RP-109171).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 133
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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