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Invitrogen™ ADSL Monoclonal Antibody (OTI2D10)
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Catalog No. PIMA525263
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100 μL
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Catalog No. Quantity
PIMA525263 100 μL
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Catalog No. PIMA525263 Supplier Invitrogen™ Supplier No. MA525263
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Description

Mouse Monoclonal Antibody

ADSL Monoclonal Antibody for Flow, IHC (P), Western Blot

ADSL (adenylosuccinate lyase), also known as AMPS, ASL or ASASE, is a 484 amino acid protein that is involved in both purine biosynthesis and in the formation of adenosine monophosphate (AMP) from inosine monophosphate. Expressed ubiquitously, ADSL catalyzes two key reactions in AMP biosynthesis, namely the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and the subsequent removal of fumarate from adenylosuccinate to yield AMP. Defects in the gene encoding ADSL are the cause of adenylosuccinase deficiency (ADSL deficiency), an autosomal recessive disorder characterized by epilepsy, growth retardation and muscular wasting. Multiple isoforms of ADSL exist due to alternative splicing events.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ADSL
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone OTI2D10
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Adsl
Gene Accession No. P30566, Q8HXY5
Gene Alias 2510006M18Rik; Adenylosuccinase; adenylosuccinate lyase; adenylosuccinate lyase 1; Adl; Adsl; AMPS; argininosuccinase; argininosuccinate lyase; Arginosuccinase; ASAL; ASase; ASL; null; test; unnamed protein product
Gene Symbols Adsl
Host Species Mouse
Immunogen Full length human recombinant protein of ADSL produced in HEK293T cell.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 101864843, 158, 315150, 474499
Target Species Canine, Cynomolgus Monkey, Human, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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