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  5. Tocris Bioscience™ (±)-ADX71743, >98%;

Tocris Bioscience™ (±)-ADX71743, >98%;
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Catalog No. 571510
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57-151-0 10 mg
57-155-0 50 mg
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Catalog No. 57-151-0 Supplier Tocris Bioscience™ Supplier No. 5715/10
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Description

Negative allosteric modulator at mGlu7; brain penetrant

Negative allosteric modulator at mGlu7 (IC50 = 300 nM). Blocks high frequency-induced LTP at SC-CA1 synapses in hippocampal slices in vitro. Increases evoked excitatory postsynaptic currents (eEPSCs) in mice. Brain penetrant.

Specifications

Quantity 10 mg
Solubility Soluble to 100mM in DMSO and to 100mM in ethanol
Formula Weight 269.34
Purity >98%
Chemical Name or Material 6-(2,4-Dimethylphenyl)-2-ethyl-6,7-dihydro-4(5H)-benzoxazolone

Safety and Handling

Recommended Storage Store at -20°C
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