AF4 Rabbit anti-Human, Polyclonal, Bioss

Rabbit Polyclonal Antibody

Supplier:  Bioss BS5958R

Catalog No. 50-198-6935

Description

Proto-oncogene AF-4 (or FEL) is a product of a chromosomal aberration of the human gene AFF1, which is associated with acute leukemias. The fusion of AF-4 on chromosome band 4q21 with the mixed lineage leukemia (MLL or HRX) gene on 11q23 results in a MLL-AF-4 chimeric transcription factor in which AF-4 contributes transcriptional effector properties and requires cell-specific accessory factors. MLL is involved in several chromosomal translocations associated with acute myeloid and lymphoid leukemia. The MLL-AF-4 fusion protein is expressed in all normal hematopoietic cells.

Specifications

• Antigen: AF4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: AFF1
• Gene Alias: 9630032B01Rik; AF4; AF4/FMR2 family member 1; AF4/FMR2 family, member 1; AFF1; ALL1-fused gene from chromosome 4 protein; AW319193; FEL; homolog of human MLLT2 unidentified; MLLT2; Mllt2h; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 2; myeloid/lymphoid or mixed-lineage leukemia translocated to 2 homolog; PBM1; pre-B-cell monocytic leukemia partner 1; Protein AF-4; Protein FEL; Proto-oncogene AF4; Rob; robotic
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 4299
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 μg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene Accession No.: P51825
• Gene Symbols: AFF1
• Immunogen: KLH conjugated synthetic peptide derived from human AF 4 protein.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG