Invitrogen™ AFF4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5103584

Catalog No. PIPA5103584

Description

Antibody detects endogenous levels of total AFF4.

The protein encoded by this gene belongs to the AF4 family of transcription factors involved in leukemia. It is a component of the positive transcription elongation factor b (P-TEFb) complex. A chromosomal translocation involving this gene and MLL gene on chromosome 11 is found in infant acute lymphoblastic leukemia with ins.

Specifications

• Antigen: AFF4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: AFF4
• Gene Alias: AF4/FMR2 family member 4; AF4/FMR2 family, member 4; AF5Q31; Aff4; Alf4; ALL1 fused gene from 5q31; ALL1-fused gene from chromosome 5q31 protein; CHOPS; HSPC092; Laf4l; LOW QUALITY PROTEIN: AF4/FMR2 family member 4; major CDK9 elongation factor-associated protein; MCEF; Protein AF-5q31; RA_m002_jsmFBA6Br
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 27125, 93736
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q9ESC8, Q9UHB7
• Gene Symbols: AFF4
• Immunogen: A synthesized peptide derived from human AFF4(Accession Q9UHB7), corresponding to amino acid residues Y1036-P1086.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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