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AFP Mouse anti-Human, Clone: C2, Abnova™

Catalog No. 89933522 Shop All Abnova Corporation Products
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Catalog No. Quantity
89-933-522 100 μg
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Catalog No. 89-933-522 Supplier Abnova Corporation Supplier No. MAB13263
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Description

Mouse monoclonal antibody raised against native human AFP.

This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. [provided by RefSeq]

Specifications

Antigen AFP
Applications Flow Cytometry, Immunofluorescence, Immunohistochemistry (PFA fixed)
Classification Monoclonal
Clone C2
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against native human AFP.
Dilution Flow Cytometry (0.5-1 ug/106 cells in 0.1 mL) Immunofluorescence (0.5-1 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1-2 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In 10mM PBS (0.05% BSA, 0.05% sodium azide).
Gene Alias FETA/HPAFP
Gene Symbols AFP
Host Species Mouse
Immunogen Native purified AFP from serum of a hepatoma patient.
Purification Method Protein A/G purification
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 174
Test Specificity This monoclonal antibody is highly specific to AFP and shows no cross-reaction with other oncofetal antigens or serum albumin.
Target Species Human
Content And Storage Store at 4°C.
Form Liquid
Isotype IgG1 κ
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