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AG 1478 hydrochloride, Tocris Bioscience™
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Catalog No. 127650
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Highly potent EGFR-kinase inhibitor

Potent and selective inhibitor of epidermal growth factor receptor kinase (IC50 values 3 nM for EGFR and > 100 μM for ErbB2 and PDGFR). Inhibits proliferation of NCI-H2170 NSCLC cells in vitro (IC50 = 1 μM).

Chemical Identifiers

CAS 170449-18-0
Molecular Formula C16H15Cl2N3O2
Molecular Weight (g/mol) 352.215
InChI Key WDJDYIUSDDVWKB-UHFFFAOYSA-N
Synonym n-3-chlorophenyl-6,7-dimethoxyquinazolin-4-amine hydrochloride, tyrphostin hydrochloride, 6,7-dimethoxy-4-n-3-chlorophenyl amino quinazoline hydrochloride, ag 1478 hydrochloride, n-3-chlorophenyl-6,7-dimethoxy-4-quinazolinamine monohydrochloride, 4-3-chloroanilino-6,7-dimethoxyquinazoline hcl, 4-quinazolinamine, n-3-chlorophenyl-6,7-dimethoxy-, monohydrochloride, rtki cpd, ag1478 hydrochloride, ag-1478 hydrochloride/
PubChem CID 3035187
IUPAC Name N-(3-chlorophenyl)-6,7-dimethoxyquinazolin-4-amine;hydrochloride
SMILES COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=CC=C3)Cl)OC.Cl

Specifications

Quantity 50 mg
Formula Weight 352.22
Percent Purity >98%
Chemical Name or Material AG 1478 hydrochloride

Safety and Handling

Recommended Storage Desiccate at -20°C
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