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AG 825, Tocris Bioscience™

Catalog No. 155550
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15-555-0 50 mg
15-551-0 10 mg
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Catalog No. 15-555-0 Supplier R&D Systems Supplier No. 1555/50
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Description

Selective ErbB2 inhibitor

Selective ErbB2 inhibitor (IC50 values are 0.15 and 19 μM at ErbB2 and ErbB1 respectively). Preferentially triggers p38 MAP kinase-dependent apoptosis in androgen-independent prostate cancer cells.

Chemical Identifiers

CAS 149092-50-2
Molecular Formula C19H15N3O3S2
Molecular Weight (g/mol) 397.47
MDL Number MFCD01074971
InChI Key KXDONFLNGBQLTN-UHFFFAOYSA-N
Synonym tyrphostin ag 825, tyrphostin c15, 4-hydroxy-3-methoxy-5-benzothiazolylthiomethyl benzylidenecyanoacetamide, 5-benzothiazol-2-yl thiomethyl-4-hydroxy-3-methoxybenzylidenecyanoacetamide, 2e-3-3-1,3-benzothiazol-2-ylsulfanyl methyl-4-hydroxy-5-methoxyphenyl-2-cyanoprop-2-enamide, tocris-1555, biomolki_000008, biomolki2_000018, bmk1-b8, tyrphostin ag
PubChem CID 6091659
ChEBI CHEBI:75405
IUPAC Name 3-{3-[(1,3-benzothiazol-2-ylsulfanyl)methyl]-4-hydroxy-5-methoxyphenyl}-2-cyanoprop-2-enamide
SMILES COC1=CC(C=C(C#N)C(N)=O)=CC(CSC2=NC3=CC=CC=C3S2)=C1O

Specifications

Quantity 50 mg
Formula Weight 397.47
Percent Purity >98%
Chemical Name or Material AG 825

Safety and Handling

Recommended Storage Store at +4°C
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