Invitrogen™ AGBL4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5101548

Catalog No. PIPA5101548

Description

Antibody detects endogenous levels of total AGBL4.

Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes polyglutamates from the carboxy-terminus of target proteins such as MYLK. Mediates deglutamylation of CGAS, regulating the antiviral activity of CGAS. Acts as a long-chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the branching point glutamate, a process catalyzed by AGBL5/CCP5. [UniProt].

Specifications

• Antigen: AGBL4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: AGBL4
• Gene Alias: AGBL4; ATP/GTP binding protein like 4; ATP/GTP binding protein-like 4; ATP/GTP-binding protein-like 4; CCP6; Cytosolic carboxypeptidase 6
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 84871
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q5VU57
• Gene Symbols: AGBL4
• Immunogen: A synthesized peptide derived from human AGBL4(Accession Q5VU57), corresponding to amino acid residues Y437-K487.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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