Invitrogen™ AGBL4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA531572

Catalog No. PIPA531572

Description

Recommended positive controls: A549, HepG2. Predicted reactivity: Mouse (93%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes polyglutamates from the carboxy-terminus of target proteins such as MYLK. Mediates deglutamylation of CGAS, regulating the antiviral activity of CGAS. Acts as a long-chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the branching point glutamate, a process catalyzed by AGBL5/CCP5. [UniProt].

Specifications

• Antigen: AGBL4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: AGBL4
• Gene Alias: AGBL4; ATP/GTP binding protein like 4; ATP/GTP binding protein-like 4; ATP/GTP-binding protein-like 4; CCP6; Cytosolic carboxypeptidase 6
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 84871
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.7 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q5VU57
• Gene Symbols: AGBL4
• Immunogen: Recombinant protein encompassing a sequence within the center region of human AGBL4. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG