Invitrogen™ AGK Monoclonal Antibody (9A3B1)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA534959

Catalog No. PIMA534959

Description

Immunogen sequence: MTVFFKTLRN HWKKTTAGLC LLTWGGHWLY GKHCDNLLRR AACQEAQVFG NQLIPPNAQV KKATVFLNPA ACKGKARTLF EKNAAPILHL SGMDVTIVKT DYEGQAKKLL ELMENTDVII VAGGDGTLQE VVTGVLRRTD EATFSKIPIG FIPLGETSSL SHTLFAESGN KVQHITDATL AIVKGETVPL DVLQIKGEKE QPVFAMTGLR WGSFRDAGVK VSKYWYLGPL KIKAAHFFST LKEWPQTHQA SISYTGPTER PPNEPEETPV QRPSLYRRIL RRLASYWAQP QDALSQEVSP EVWKDVQLST IELSITTRNN QLDPTSKEDF LNICIEPDTI SKGDFITIGS RKVRNPKLHV EGTECLQASQ CTLLIPEGAG GSFSIDSEEY EAMPVEVKLL PRKLQFFCDP RKREQMLTSP TQ.

Lipid kinase that can phosphorylate both monoacylglycerol and diacylglycerol to form lysophosphatidic acid (LPA) and phosphatidic acid (PA), respectively. Does not phosphorylate sphingosine. Overexpression increases the formation and secretion of LPA, resulting in transactivation of EGFR and activation of the downstream MAPK signaling pathway, leading to increased cell growth.

Specifications

• Antigen: AGK
• Classification: Monoclonal
• Concentration: 0.45 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q53H12
• Gene Symbols: AGK
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-422 of human AGK (NP_060708.1).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1 κ

• Applications: ELISA, Western Blot
• Clone: 9A3B1
• Conjugate: Unconjugated
• Gene: AGK
• Gene Alias: 2610037M15Rik; 6720408I04Rik; acylglycerol kinase; acylglycerol kinase, mitochondrial; Agk; AI465370; CATC5; CTRCT38; FLJ10842; hAGK; hsMuLK; MTDPS10; Mulk; multiple substrate lipid kinase; multi-substrate lipid kinase; RGD1562046
• Host Species: Mouse
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 55750
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid