Invitrogen™ AGK Polyclonal Antibody

Catalog No.	Quantity
PIPA597316	100 μL

Catalog No. PIPA597316

Supplier: Invitrogen™ PA597316

Description

Rabbit Polyclonal Antibody

Immunogen sequence: KAAHFFSTLK EWPQTHQASI SYTGPTERPP NEPEETPVQR PSLYRRILRR LASYWAQPQD ALSQEVSPEV WKDVQLSTIE LSITTRNNQL DPTSKEDFLN ICIEPDTISK GDFITIGSRK VRNPKLHVEG TECLQASQCT LLIPEGAGGS FSIDSEEYEA MPVEVKLLPR KLQFFCDPRK REQMLTSPTQ; Positive Samples: 293T, SH-SY5Y, HepG2, HeLa, 22Rv1, BT-474, K-562, Rat brain; Cellular Location: Mitochondrion membrane.

Lipid kinase that can phosphorylate both monoacylglycerol and diacylglycerol to form lysophosphatidic acid (LPA) and phosphatidic acid (PA), respectively. Does not phosphorylate sphingosine. Overexpression increases the formation and secretion of LPA, resulting in transactivation of EGFR and activation of the downstream MAPK signaling pathway, leading to increased cell growth.

Specifications

• Antigen: AGK
• Applications: ELISA, Western Blot
• Classification: Polyclonal
• Concentration: 0.42 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: AGK
• Gene Accession No.: Q53H12
• Gene Alias: 2610037M15Rik; 6720408I04Rik; acylglycerol kinase; acylglycerol kinase, mitochondrial; Agk; AI465370; CATC5; CTRCT38; FLJ10842; hAGK; hsMuLK; MTDPS10; Mulk; multiple substrate lipid kinase; multi-substrate lipid kinase; RGD1562046
• Gene Symbols: AGK
• Host Species: Rabbit
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 233-422 of human AGK (NP_0607081).
• Purification Method: Affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 502749, 55750
• Target Species: Human, Rat
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG