Invitrogen™ AGK Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA597316

Catalog No. PIPA597316

Description

Immunogen sequence: KAAHFFSTLK EWPQTHQASI SYTGPTERPP NEPEETPVQR PSLYRRILRR LASYWAQPQD ALSQEVSPEV WKDVQLSTIE LSITTRNNQL DPTSKEDFLN ICIEPDTISK GDFITIGSRK VRNPKLHVEG TECLQASQCT LLIPEGAGGS FSIDSEEYEA MPVEVKLLPR KLQFFCDPRK REQMLTSPTQ; Positive Samples: 293T, SH-SY5Y, HepG2, HeLa, 22Rv1, BT-474, K-562, Rat brain; Cellular Location: Mitochondrion membrane.

Lipid kinase that can phosphorylate both monoacylglycerol and diacylglycerol to form lysophosphatidic acid (LPA) and phosphatidic acid (PA), respectively. Does not phosphorylate sphingosine. Overexpression increases the formation and secretion of LPA, resulting in transactivation of EGFR and activation of the downstream MAPK signaling pathway, leading to increased cell growth.

Specifications

• Antigen: AGK
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: AGK
• Gene Alias: 2610037M15Rik; 6720408I04Rik; acylglycerol kinase; acylglycerol kinase, mitochondrial; Agk; AI465370; CATC5; CTRCT38; FLJ10842; hAGK; hsMuLK; MTDPS10; Mulk; multiple substrate lipid kinase; multi-substrate lipid kinase; RGD1562046
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 502749, 55750
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.42 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q53H12
• Gene Symbols: AGK
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 233-422 of human AGK (NP_0607081).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG