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Tocris Bioscience™ AGN 193109
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Catalog No. 575810
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57-581-0 10 mg
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Description

High affinity pan-RAR antagonist

AGN 193109 is a high affinity pan-retinoic acid receptor (RAR) antagonist (Kd values are 2, 2 and 3 nM at RARα, RARβ and RARγ, respectively). Exhibits no significant affinity for retinoic X receptors. AGN 193109 promotes the differentiation from mouse embryonic stem cells into paraxial mesoderm. AGN 193109 suppresses primary human cardiovascular smooth muscle cell calcification.

AGN 193109 synthesized to Ancillary Material Grade also available.

Specifications

CAS 171746-21-7
Quantity 10 mg
Target Retinoic Acid Receptor
Molecular Formula C28H24O2
Formula Weight 392.49g/mol
Product Type Antagonist

For Research Use Only

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