Invitrogen™ AGO1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5120966

Catalog No. PIPA5120966

Description

Positive test controls include: 293T, MCF7, Mouse lung, Mouse spleen, Rat kidney. The target is usually found in the following locations: Cytoplasm, P-body. Immunogen sequence: MEAGPSGAAA GAYLPPLQQV FQAPRRPGIG TVGKPIKLLA NYFEVDIPKI DVYHYEVDIK PDKCPRRVNR EVVEYMVQHF KPQIFGDRKP VYDGKKNIYT VTALPIGNER VDFEVTIPGE GKDRIFKVSI KWLAIVSWRM LHEALVSGQI PVPLESVQAL DVAMRHLASM.

AGO1 is a member of the Argonaute family of proteins which play a role in RNA interference. The protein is highly basic, and contains a PAZ domain and a PIWI domain. It may interact with dicer1 and play a role in short-interfering-RNA-mediated gene silencing. AGO1 binds to miRNAs or siRNAs and represses the translation of mRNAs.

Specifications

• Antigen: AGO1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Ago1
• Gene Alias: AGO1; argonaute 1; argonaute 1, RISC catalytic component; argonaute RISC catalytic component 1; argonaute RISC catalytic subunit 1; argonaute1; EIF2C; eIF2C 1; eIF-2C 1; EIF2C1; Eukaryotic translation initiation factor 2C 1; eukaryotic translation initiation factor 2C, 1; GERP95; Golgi Endoplasmic Reticulum protein 95 kDa; hAgo1; mAgo1; Piwi/Argonaute family protein meIF2C1; Protein argonaute-1; putative RNA-binding protein Q99; Q99
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 236511, 26523, 313594
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.21 mg/mL
• Formulation: PBS with 50% glycerol and 0.09% sodium azide; pH 7.3
• Gene Accession No.: Q8CJG1, Q9UL18
• Gene Symbols: Ago1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-170 of human AGO1 (NP_036331.1).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG