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  6. Ago3 Monoclonal Antibody (4B1-F6), Active Motif™ 

Ago3 Monoclonal Antibody (4B1-F6), Active Motif™
SDP

Catalog No. 501992852
Encompass
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50-199-2852 100 μg
50-199-2853 10 μg
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Catalog No. 50-199-2852 Supplier Active Motif Supplier No. 39787
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Description

Mouse Monoclonal Antibody

AGO3 (protein argonaute-3) is required to RNA-mediated gene silencing (RNAi). It binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. AGO3 is proposed to be involved in stabilization of small RNA derivates (riRNA) derived from processed RNA polymerase III-transcribed Alu repeats containing a DR2 retinoic acid response element (RARE) in stem cells and in the subsequent riRNA-dependent degradation of a subset of RNA polymerase II-transcribed coding mRNAs by recruiting a mRNA decapping complex involving EDC4.

Specifications

Antigen Ago3
Applications ChIP Assay, Immunocytochemistry, Immunofluorescence, Immunoprecipitation
Classification Monoclonal
Clone 4B1-F6
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene AGO3
Gene Accession No. Q9H9G7
Gene Alias AGO3; argonaute 3; argonaute 3, RISC catalytic component; Argonaute RISC catalytic component 3; argonaute RISC catalytic subunit 3; Argonaute3; AW048688; BOS_3617; C130014L07Rik; eIF2C 3; eIF-2C 3; EIF2C1; EIF2C3; Eukaryotic translation initiation factor 2C 3; eukaryotic translation initiation factor 2C, 1; eukaryotic translation initiation factor 2C, 3; hAgo3; mAgo3; Piwi/argonaute family protein meIF2C3; Protein argonaute-3
Gene Symbols AGO3
Host Species Mouse
Immunogen This Ago3 (Argonaute 3) antibody was raised against a recombinant protein corresponding to amino acids 1-175 of human Ago3.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 192669
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2a
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