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Invitrogen™ AGPAT2 Polyclonal Antibody
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Catalog No. PIPA5112352
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PIPA5112352 100 μL
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Catalog No. PIPA5112352 Supplier Invitrogen™ Supplier No. PA5112352
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Description

Rabbit Polyclonal Antibody

AGPAT2 Polyclonal Antibody for Western Blot, IHC (P), ELISA

Lysophospholipid acyltransferases (LPLATs) catalyse the addition of fatty acyl moieties to the glycerol backbone of lysophospholipids. In addition to playing a crutial role in the synthesis of structural membrane components the LPLATs are also implicated in cellular signalling responses for cytokines, growth factors and other agonists. Cellular signalling through the interleukin 1 receptor in human mesangial cells and EL-4 cells proceeds by the activation of lysophosphatidic acid acyltransferase (LPAAT). Activation of LPAAT by interleukin 1 results in the generation of unsaturated phosphatidic acid species, that are crucial to the generation of diacylglycerol and interleukin 1 signalling. LPLATs are also involved in signalling for increased interleukin 2 synthesis through the T cell antigen receptor. Activation of T-cells via anti-CD3 stimulation has been shown to increase incorporation of polyunsaturated fatty acids intophosphatidylcholine via lysophosphatidylcholine acyltransferase.Activation of this enzyme is essential for the sustained activationand translocation of protein kinase C.
TRUSTED_SUSTAINABILITY

Specifications

Antigen AGPAT2
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.55 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene AGPAT2
Gene Accession No. O15120
Gene Alias 1-acylglycerol-3-phosphate O-acyltransferase 2; 1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta); 1-acyl-sn-glycerol-3-phosphate acyltransferase beta; 1-AGP acyltransferase 2; 1-AGPAT 2; 1-AGPAT2; 2510002J07Rik; AGPAT2; AV000834; BSCL; BSCL1; LPAAB; LPAAT-beta; lysophosphatidic acid acyltransferase beta; lysophosphatidic acid acyltransferase-beta; testicular tissue protein Li 143
Gene Symbols AGPAT2
Host Species Rabbit
Immunogen Recombinant Human 1-acyl-sn-glycerol-3-phosphate acyltransferase beta protein (199-278AA).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10555
Target Species Human
Content And Storage -20°C or -80°C if preferred
Product Type Antibody
Form Liquid
Isotype IgG
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