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Invitrogen™ AGR2/AGR3 Monoclonal Antibody (AGR3.4)
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Catalog No. PIMA110047
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100 μg
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PIMA110047 100 μg
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Catalog No. PIMA110047 Supplier Invitrogen™ Supplier No. MA110047
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Mouse Monoclonal Antibody

This antibody recognizes the PLMII epitope of AGR3 (AG3) and AGR2 (AG2) proteins (19-20 kDa); secreted cytoplasmic proteins which can serve as markers of carcinogenesis.

AGR2 (Anterior Gradient 2), also known as AG2 (hAG-2, HAG2 in human), or GOB-4, and AGR3 (Anterior Gradient 3), also known as AG3 (hAG-3, HAG3 in human), or BCMP11, are secreted cytoplasmic proteins which are involved in metastasis induction and p53 tumour supressor inhibition. They may serve as molecular markers and potential therapeutic targets for hormone-responsive breast tumours; AGR2 was reported also as a marker of other carcinomas. Xenopus homolog of these proteins is associated with anteroposterior fate determination during early development.
TRUSTED_SUSTAINABILITY

Specifications

Antigen AGR2/AGR3
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone AGR3.4
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.2% BSA and 15mM sodium azide; pH 7.4
Gene AGR2
Gene Accession No. O95994, Q8TD06
Gene Alias AG2; AG-2; AG3; AG-3; AGR2; AGR3; anterior gradient 2, protein disulphide isomerase family member; Anterior gradient 3 homolog; anterior gradient 3, protein disulphide isomerase family member; anterior gradient homolog 2; anterior gradient homolog 3; anterior gradient protein 2 homolog; Anterior gradient protein 3; anterior gradient protein 3 homolog; BCMP11; Breast cancer membrane protein 11; epididymis secretory protein Li 116; GOB-4; HAG-2; HAG3; hAG-3; HEL-S-116; HPC8; PDIA17; PDIA18; protein disulfide isomerase family A, member 17; protein disulfide isomerase family A, member 18; secreted cement gland homolog; secreted cement gland protein XAG-2 homolog; UNQ515/PRO1030; UNQ642/PRO1272; XAG-2
Gene Symbols AGR2, AGR3
Host Species Mouse
Immunogen Purified human AGR3 protein.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10551, 155465
Target Species Human
Content And Storage 4°C, do not freeze
Product Type Antibody
Form Liquid
Isotype IgG1
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