Invitrogen™ AGR2/AGR3 Monoclonal Antibody (AGR3.4)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA110047

Catalog No. PIMA110047

Description

This antibody recognizes the PLMII epitope of AGR3 (AG3) and AGR2 (AG2) proteins (19-20 kDa); secreted cytoplasmic proteins which can serve as markers of carcinogenesis.

AGR2 (Anterior Gradient 2), also known as AG2 (hAG-2, HAG2 in human), or GOB-4, and AGR3 (Anterior Gradient 3), also known as AG3 (hAG-3, HAG3 in human), or BCMP11, are secreted cytoplasmic proteins which are involved in metastasis induction and p53 tumour supressor inhibition. They may serve as molecular markers and potential therapeutic targets for hormone-responsive breast tumours; AGR2 was reported also as a marker of other carcinomas. Xenopus homolog of these proteins is associated with anteroposterior fate determination during early development.

Specifications

• Antigen: AGR2/AGR3
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.2% BSA and 15mM sodium azide; pH 7.4
• Gene Accession No.: O95994, Q8TD06
• Gene Symbols: AGR2, AGR3
• Immunogen: Purified human AGR3 protein.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: AGR3.4
• Conjugate: Unconjugated
• Gene: AGR2
• Gene Alias: AG2; AG-2; AG3; AG-3; AGR2; AGR3; anterior gradient 2, protein disulphide isomerase family member; Anterior gradient 3 homolog; anterior gradient 3, protein disulphide isomerase family member; anterior gradient homolog 2; anterior gradient homolog 3; anterior gradient protein 2 homolog; Anterior gradient protein 3; anterior gradient protein 3 homolog; BCMP11; Breast cancer membrane protein 11; epididymis secretory protein Li 116; GOB-4; HAG-2; HAG3; hAG-3; HEL-S-116; HPC8; PDIA17; PDIA18; protein disulfide isomerase family A, member 17; protein disulfide isomerase family A, member 18; secreted cement gland homolog; secreted cement gland protein XAG-2 homolog; UNQ515/PRO1030; UNQ642/PRO1272; XAG-2
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 10551, 155465
• Content And Storage: 4°C, do not freeze
• Form: Liquid